Superiority vs non-inferiority trials - Methodology of superiority vs equivalence trials and
Review Methodology of superiority vs. equivalence trials and non-inferiority trials Erik Christensen* Clinic of Internal Medicine I, Bispebjerg University Hospital, Bispebjerg Bakke 23, DK-2400 Copenhagen NV, Copenhagen, Denmark
Statistical Assessment of Superiority, Equivalence and Non-Inferiority in Clinical Trials Les Huson. As confidence intervals have become increasingly widely employed,
Equivalence vs. Non-Inferiority –Are equivalence trials always feasible and –How likely is clinically relevant superiority?
Both non-inferiority and superiority tests are examples of directional (one-sided) tests and their power and sample size could be calculated using the .
Superiority, non-inferiority, equivalence studies - what is the difference? 1. Superiority-Equivalence-Non-Inferiority Trials: What does it all mean?
Nathan Teuscher defines the following clinical drug trial designs—Non-inferiority vs. Superiority vs. Equivalence- as well as when to use each trial design.